Death brings new life to muscle

DAMPs from Cell Death to New Life

Our body handles tissue damage by activating the immune system in response to intracellular molecules released by injured tissues [damage-associated molecular patterns (DAMPs)], in a similar way as it detects molecular motifs conserved in pathogens (pathogen-associated molecular patterns). DAMPs are molecules that have a physiological role inside the cell, but acquire additional functions when ...

Photo Animation Brings Scientists Back to Life in the Classroom†

Systems Biology Brings Life Sciences Closer

The China-UK Systems Biology Workshop 2005 was held during June 20–21 in the National Science Park of Zhejiang University, Hangzhou, China. It was organized by the Institute of Bioinformatics, Zhejiang University, and was initiated by Prof. Dr. Jun Zhu (Zhejiang University) and Prof. Dr. John Findlay (University of Leeds, UK). The workshop was part of the program called UK-China Partners in Sci...

A new year brings new opportunities.

As we usher in the 29th year of publishing JTI, it is a fitting time to reflect on the past year of the journal and to look forward to the opportunities that lie ahead in the coming year. In 2013, we strategically published the largest annual number and variety of cardiopulmonary imaging review articles in the journal’s history. With this issue, we continue this trend with the publication of se...

Euarchontan Opsin Variation Brings New Focus to Primate Origins

Debate on the adaptive origins of primates has long focused on the functional ecology of the primate visual system. For example, it is hypothesized that variable expression of short- (SWS1) and middle-to-long-wavelength sensitive (M/LWS) opsins, which confer color vision, can be used to infer ancestral activity patterns and therefore selective ecological pressures. A problem with this approach ...